BBC3 is altered in 0.50% of all cancers with colon adenocarcinoma, breast invasive ductal carcinoma, conventional glioblastoma multiforme, lung adenocarcinoma, and high grade ovarian serous adenocarcinoma having the greatest prevalence of alterations .
The most common alterations in BBC3 are BBC3 Loss (0.11%), BBC3 Amplification (0.05%), BBC3 R223Q (0.01%), BBC3 X126_splice (0.01%), and BBC3 A254T (0.01%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.