Biomarkers /

CLIP2

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Overview

Location [1]
7q11.23
Protein [2]
CAP-Gly domain-containing linker protein 2
Synonyms [1]
WSCR3, WBSCR3, CLIP-115, CLIP, WBSCR4, WSCR4, CYLN2

CLIP2 is altered in 0.15% of all cancers with astrocytoma, low-grade glioma, NOS, pancreatic adenocarcinoma, pilocytic astrocytoma, and thyroid gland papillary carcinoma having the greatest prevalence of alterations [3].

CLIP2 GENIE Cases - Top Diseases

The most common alterations in CLIP2 are CLIP2-BRAF Fusion (0.14%) and CLIP2-FGFR1 Fusion (0.02%) [3].

CLIP2 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.