DDX41 is altered in 0.99% of all cancers with conventional glioblastoma multiforme, anaplastic oligodendroglioma, cutaneous melanoma, endometrial endometrioid adenocarcinoma, and skin squamous cell carcinoma having the greatest prevalence of alterations .
The most common alterations in DDX41 are DDX41 P189S (0.18%), DDX41 A295T (0.07%), DDX41 A401V (0.09%), DDX41 A477T (0.07%), and DDX41 D351N (0.07%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.