Location [1]
Protein [2]
Transcription factor E2F3
Synonyms [1]

E2F3 is altered in 1.06% of all cancers with bladder urothelial carcinoma, lung adenocarcinoma, breast invasive ductal carcinoma, endometrial endometrioid adenocarcinoma, and colon adenocarcinoma having the greatest prevalence of alterations [3].

E2F3 GENIE Cases - Top Diseases

The most common alterations in E2F3 are E2F3 Amplification (0.48%), E2F3 Loss (0.03%), E2F3 R134* (0.01%), E2F3 V25A (0.01%), and E2F3 F44L (0.01%) [3].

E2F3 GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.