Biomarkers /

ENG

Back to Biomarkers List
Associated Diseases

Overview

Location [1]
9q34.11
Protein [2]
Endoglin
Synonyms [1]
HHT1, ORW1, END

ENG is altered in 0.83% of all cancers with lung adenocarcinoma, colon adenocarcinoma, endometrial endometrioid adenocarcinoma, bladder urothelial carcinoma, and clear cell renal cell carcinoma having the greatest prevalence of alterations [3].

ENG GENIE Cases - Top Diseases

The most common alterations in ENG are ENG Fusion (0.04%), ENG H108Y (0.06%), ENG Amplification (0.05%), ENG R192H (0.05%), and ENG R197W (0.05%) [3].

ENG GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.