Location [1]
Protein [2]
Ephrin type-B receptor 6
Synonyms [1]

EPHB6 is altered in 2.03% of all cancers with high grade ovarian serous adenocarcinoma, melanoma, bladder urothelial carcinoma, conventional glioblastoma multiforme, and gastric adenocarcinoma having the greatest prevalence of alterations [3].

EPHB6 GENIE Cases - Top Diseases

The most common alterations in EPHB6 are EPHB6 Mutation (2.03%), EPHB6 R920C (0.24%), EPHB6 A562T (0.26%), EPHB6 A903D (0.85%), and EPHB6 A990G (0.39%) [3].

EPHB6 GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.