Biomarkers /

FAM114A2

Back to Biomarkers List
Associated Diseases

Overview

Location [1]
5q33.2
Protein [2]
Protein FAM114A2
Synonyms [1]
133K02, C5orf3

FAM114A2 is altered in 0.06% of all cancers with low-grade glioma, NOS, pancreatic adenocarcinoma, pilocytic astrocytoma, thyroid gland papillary carcinoma, and astrocytoma having the greatest prevalence of alterations [3].

FAM114A2 GENIE Cases - Top Diseases

The most common alterations in FAM114A2 are FAM114A2-BRAF Fusion (0.14%) and FAM114A2-AURKA Fusion (0.00%) [3].

FAM114A2 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.