Overview

Location [1]
17q25.1
Protein [2]
Growth factor receptor-bound protein 2
Synonyms [1]
Grb3-3, MST084, EGFRBP-GRB2, ASH, NCKAP2, MSTP084

GRB2 is altered in 0.00% of all cancers with invasive breast carcinoma having the greatest prevalence of alterations [3].

GRB2 GENIE Cases - Top Diseases

The most common alteration in GRB2 is GRB2-SOX9 Fusion (0.00%) [3].

GRB2 GENIE Cases - Top Alterations

Significance of GRB2 in Diseases

Hepatocellular Carcinoma +

Non-Small Cell Lung Carcinoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.