Overview

Location [1]
7p15.2
Protein [2]
Heterogeneous nuclear ribonucleoproteins A2/B1
Synonyms [1]
IBMPFD2, HNRNPA2, HNRPA2, SNRPB1, HNRPA2B1, RNPA2, HNRPB1, HNRNPB1

HNRNPA2B1 is altered in 0.03% of all cancers with prostate adenocarcinoma, breast invasive ductal carcinoma, anal squamous cell carcinoma, bladder urothelial carcinoma, and colon adenocarcinoma having the greatest prevalence of alterations [3].

HNRNPA2B1 GENIE Cases - Top Diseases

The most common alterations in HNRNPA2B1 are HNRNPA2B1-ETV1 Fusion (0.02%) and HNRNPA2B1-NTRK3 Fusion (0.03%) [3].

HNRNPA2B1 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.