HSPA5 is altered in 0.99% of all cancers with conventional glioblastoma multiforme, cutaneous melanoma, neuroendocrine carcinoma, NOS, anaplastic oligodendroglioma, and atypical myeloid disorder having the greatest prevalence of alterations .
The most common alterations in HSPA5 are HSPA5 A208D (0.07%), HSPA5 A325T (0.09%), HSPA5 A8S (0.09%), HSPA5 D238V (0.07%), and HSPA5 D615V (0.09%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.