Location [1]
Protein [2]
KN motif and ankyrin repeat domain-containing protein 1
Synonyms [1]

KANK1 is altered in 0.02% of all cancers with breast invasive ductal carcinoma, colon adenocarcinoma, bladder urothelial carcinoma, colorectal neuroendocrine carcinoma, and conventional glioblastoma multiforme having the greatest prevalence of alterations [3].

KANK1 GENIE Cases - Top Diseases

The most common alterations in KANK1 are KANK1-NTRK3 Fusion (0.03%) and KANK1-DOCK8 Fusion (0.02%) [3].

KANK1 GENIE Cases - Top Alterations

Significance of KANK1 in Diseases

Adenocarcinoma Of The Gastroesophageal Junction +

Gastric Adenocarcinoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.