Biomarkers /

KDM3A

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Overview

Location [1]
2p11.2
Protein [2]
Lysine-specific demethylase 3A
Synonyms [1]
JHMD2A, TSGA, JMJD1, JHDM2A, JMJD1A

KDM3A is altered in 1.28% of all cancers with breast invasive ductal carcinoma, breast neoplasm, breast invasive lobular carcinoma, mixed lobular and ductal breast carcinoma, and mucinous breast carcinoma having the greatest prevalence of alterations [3].

KDM3A GENIE Cases - Top Diseases

The most common alterations in KDM3A are KDM3A Mutation (0.95%), KDM3A Amplification (0.25%), KDM3A A1103G (0.04%), KDM3A E355K (0.04%), and KDM3A G1153E (0.04%) [3].

KDM3A GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.