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LAMP1

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Overview

Location [1]
13q34
Protein [2]
Lysosome-associated membrane glycoprotein 1
Synonyms [1]
LAMPA, CD107a, LGP120

LAMP1 is altered in 1.35% of all cancers with colon adenocarcinoma, high grade ovarian serous adenocarcinoma, breast invasive ductal carcinoma, ovarian carcinosarcoma, and cervical mucinous adenocarcinoma, gastric type having the greatest prevalence of alterations [3].

LAMP1 GENIE Cases - Top Diseases

The most common alterations in LAMP1 are LAMP1 A26V (0.53%), LAMP1 A265V (0.20%), LAMP1 A294G (0.26%), LAMP1 A313T (0.22%), and LAMP1 A327V (0.39%) [3].

LAMP1 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.