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LRRFIP1

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Overview

Location [1]
2q37.3
Protein [2]
Leucine-rich repeat flightless-interacting protein 1
Synonyms [1]
HUFI-1, GCF-2, TRIP, FLAP-1, FLIIAP1, FLAP1, GCF2

LRRFIP1 is altered in 0.21% of all cancers with breast invasive ductal carcinoma, colon adenocarcinoma, dysembryoplastic neuroepithelial tumor, high grade ovarian serous adenocarcinoma, and invasive breast carcinoma having the greatest prevalence of alterations [3].

LRRFIP1 GENIE Cases - Top Diseases

The most common alterations in LRRFIP1 are LRRFIP1-FGFR1 Fusion (0.22%) and LRRFIP1-ALK Fusion (0.09%) [3].

LRRFIP1 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.