Biomarkers /

MAGEA1

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Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
Xq28
Protein [2]
Melanoma-associated antigen 1
Synonyms [1]
CT1.1, MAGE1

MAGEA1 is altered in 0.65% of all cancers with lung adenocarcinoma, cholangiocarcinoma, desmoplastic melanoma, endometrial serous adenocarcinoma, and esophageal adenocarcinoma having the greatest prevalence of alterations [3].

MAGEA1 GENIE Cases - Top Diseases

The most common alterations in MAGEA1 are MAGEA1 C174R (0.20%), MAGEA1 D53H (0.22%), MAGEA1 G308* (0.22%), MAGEA1 G87E (0.22%), and MAGEA1 R118Q (0.22%) [3].

MAGEA1 GENIE Cases - Top Alterations

Clinical Trials

View Clinical Trials for MAGEA1

Significance of MAGEA1 in Diseases

Malignant Solid Tumor +

Breast Carcinoma +

Non-Small Cell Lung Carcinoma +

Urothelial Carcinoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.