Location [1]
Protein [2]
Mitogen-activated protein kinase kinase kinase 13
Synonyms [1]

MAP3K13 is altered in 1.50% of all cancers with breast invasive ductal carcinoma, squamous cell lung carcinoma, lung adenocarcinoma, colon adenocarcinoma, and cutaneous melanoma having the greatest prevalence of alterations [3].

MAP3K13 GENIE Cases - Top Diseases

The most common alterations in MAP3K13 are MAP3K13 Amplification (0.60%), MAP3K13 Loss (0.02%), MAP3K13 R278C (0.02%), MAP3K13 A465V (0.01%), and MAP3K13 A189V (0.01%) [3].

MAP3K13 GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.