MAPK8 is altered in 0.45% of all cancers with cervical squamous cell carcinoma, colon adenocarcinoma, colorectal adenocarcinoma, endometrial endometrioid adenocarcinoma, and high grade ovarian serous adenocarcinoma having the greatest prevalence of alterations .
The most common alterations in MAPK8 are MAPK8 Mutation (0.45%), MAPK8 S394P (0.77%), MAPK8 V383M (0.77%), MAPK8 V399M (0.77%), and MAPK8 A419S (0.39%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.