MBD4 is altered in 1.54% of all cancers with colon adenocarcinoma, melanoma, lung adenocarcinoma, breast invasive ductal carcinoma, and glioblastoma having the greatest prevalence of alterations .
The most common alterations in MBD4 are MBD4 A70T (0.08%), MBD4 V228L (0.06%), MBD4 K518R (0.06%), MBD4 X471_splice (0.06%), and MBD4 Fusion (0.03%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.