Biomarkers /

PAN3

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Overview

Location [1]
13q12.2
Protein [2]
PAN2-PAN3 deadenylation complex subunit PAN3
Synonyms [1]
-

PAN3 is altered in 0.02% of all cancers with prostate adenocarcinoma, anal squamous cell carcinoma, breast invasive ductal carcinoma, cancer of unknown primary, NOS, and invasive breast carcinoma having the greatest prevalence of alterations [3].

PAN3 GENIE Cases - Top Diseases

The most common alterations in PAN3 are PAN3-NTRK2 Fusion (0.04%) and PAN3-FLT3 Fusion (0.00%) [3].

PAN3 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.