Biomarkers /

PTPRR

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Overview

Location [1]
12q15
Protein [2]
Receptor-type tyrosine-protein phosphatase R
Synonyms [1]
PCPTP1, EC-PTP, PTP-SL, PTPRQ, PTPBR7

PTPRR is altered in 0.04% of all cancers with breast invasive ductal carcinoma, invasive breast carcinoma, lung adenocarcinoma, appendix adenocarcinoma, and colon adenocarcinoma having the greatest prevalence of alterations [3].

PTPRR GENIE Cases - Top Diseases

The most common alterations in PTPRR are PTPRR-MDM2 Fusion (0.00%), PTPRR-SMARCD1 Fusion (0.01%), and PTPRR-STAT6 Fusion (0.02%) [3].

PTPRR GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.