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RPS6KC1

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Associated Diseases

Overview

Location [1]
1q32.3
Protein [2]
Ribosomal protein S6 kinase delta-1
Synonyms [1]
S6PKh1, humS6PKh1, S6K-delta-1, RPK118, RSKL1

RPS6KC1 is altered in 0.01% of all cancers with adenocarcinoma of unknown primary, colon adenocarcinoma, conventional glioblastoma multiforme, high grade ovarian serous adenocarcinoma, and large cell/anaplastic medulloblastoma having the greatest prevalence of alterations [3].

RPS6KC1 GENIE Cases - Top Diseases

The most common alterations in RPS6KC1 are RPS6KC1-AKT3 Fusion (0.05%), RPS6KC1-FANCL Fusion (0.02%), and RPS6KC1-VEGFA Fusion (0.00%) [3].

RPS6KC1 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.