Location [1]
Protein [2]
Synonyms [1]

RSPO3 is altered in 0.37% of all cancers with colon adenocarcinoma, melanoma, lung adenocarcinoma, endometrial endometrioid adenocarcinoma, and adenocarcinoma of unknown primary having the greatest prevalence of alterations [3].

RSPO3 GENIE Cases - Top Diseases

The most common alterations in RSPO3 are RSPO3 Fusion (0.11%), RSPO3-PTPRK Fusion (0.08%), RSPO3 Amplification (0.03%), RSPO3 G215E (0.04%), and RSPO3 Loss (0.05%) [3].

RSPO3 GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.