Biomarkers /

SORBS1

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Associated Diseases

Overview

Location [1]
10q24.1
Protein [2]
Sorbin and SH3 domain-containing protein 1
Synonyms [1]
R85FL, SH3D5, CAP, SH3P12, SORB1, FLAF2

SORBS1 is altered in 0.07% of all cancers with cholangiocarcinoma, adenocarcinoma of unknown primary, adenocarcinoma of the gastroesophageal junction, breast invasive ductal carcinoma, and esophageal adenocarcinoma having the greatest prevalence of alterations [3].

SORBS1 GENIE Cases - Top Diseases

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.