Biomarkers /

SP3

Back to Biomarkers List

Overview

Location [1]
2q31.1
Protein [2]
Transcription factor Sp3
Synonyms [1]
SPR2

SP3 is altered in 0.04% of all cancers with colon adenocarcinoma, astrocytoma, breast invasive ductal carcinoma, clear cell renal cell carcinoma, and dermatofibrosarcoma protuberans having the greatest prevalence of alterations [3].

SP3 GENIE Cases - Top Diseases

The most common alteration in SP3 is SP3-FGFR1 Fusion (0.01%) [3].

SP3 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.