Overview

Location [1]
2p22.2
Protein [2]
Striatin
Synonyms [1]
STRN1, PPP2R6A, SG2NA

STRN is altered in 0.13% of all cancers with glioblastoma, lung adenocarcinoma, pancreatic adenocarcinoma, breast invasive ductal carcinoma, and colon adenocarcinoma having the greatest prevalence of alterations [3].

STRN GENIE Cases - Top Diseases

The most common alterations in STRN are STRN-PDGFRA Fusion (0.17%), STRN-ALK Fusion (0.06%), STRN-NTRK2 Fusion (0.02%), STRN-NTRK3 Fusion (0.03%), and STRN-PTCH1 Fusion (0.01%) [3].

STRN GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.