Biomarkers /

TENM4

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Associated Diseases

Overview

Location [1]
11q14.1
Protein [2]
Teneurin-4
Synonyms [1]
TEN4, Doc4, ten-4, TNM4, Ten-M4, ETM5, ODZ4

TENM4 is altered in 0.10% of all cancers with breast invasive ductal carcinoma, invasive breast carcinoma, lung adenocarcinoma, adenocarcinoma of unknown primary, and bladder urothelial carcinoma having the greatest prevalence of alterations [3].

TENM4 GENIE Cases - Top Diseases

The most common alterations in TENM4 are TENM4-NRG1 Fusion (0.38%) and TENM4-MLH1 Fusion (0.03%) [3].

TENM4 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.