Overview

Location [1]
3q13.31
Protein [2]
T-cell immunoreceptor with Ig and ITIM domains
Synonyms [1]
VSTM3, WUCAM, VSIG9

Significance of TIGIT in Diseases

Adenocarcinoma Of The Gastroesophageal Junction +

Cervical Carcinoma +

Endometrial Carcinoma +

Fallopian Tube Carcinoma +

Gastric Adenocarcinoma +

Head And Neck Squamous Cell Carcinoma +

High Grade Ovarian Serous Adenocarcinoma +

Malignant Solid Tumor +

Ovarian Endometrioid Adenocarcinoma +

Primary Peritoneal Carcinoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.