Overview

Location [1]
1p36.11
Protein [2]
E3 ubiquitin-protein ligase TRIM63
Synonyms [1]
MURF2, SMRZ, IRF, RNF28, MURF1

TRIM63 is altered in 0.02% of all cancers with sarcoma, NOS, breast invasive ductal carcinoma, cutaneous melanoma, gastric adenocarcinoma, and pancreatic acinar cell carcinoma having the greatest prevalence of alterations [3].

TRIM63 GENIE Cases - Top Diseases

The most common alteration in TRIM63 is TRIM63-NTRK1 Fusion (0.02%) [3].

TRIM63 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.