Location [1]
Protein [2]
Proto-oncogene vav
Synonyms [1]

VAV1 is altered in 0.83% of all cancers with diffuse large B-cell lymphoma, not otherwise specified, follicular lymphoma, angioimmunoblastic T-cell lymphoma, peripheral T-cell lymphoma, not otherwise specified, and B-cell lymphoblastic leukemia/lymphoma having the greatest prevalence of alterations [3].

VAV1 GENIE Cases - Top Diseases

The most common alterations in VAV1 are VAV1 Loss (0.33%), VAV1 Amplification (0.14%), VAV1 E740* (0.05%), VAV1 A513T (0.02%), and VAV1 D161E (0.02%) [3].

VAV1 GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.