Overview

Location [1]
3q13.31
Protein [2]
Zinc finger and BTB domain-containing protein 20
Synonyms [1]
HOF, DPZF, PRIMS, ODA-8S, ZNF288

ZBTB20 is altered in 0.18% of all cancers with conventional glioblastoma multiforme, colorectal adenocarcinoma, endometrial endometrioid adenocarcinoma, skin squamous cell carcinoma, and anaplastic astrocytoma having the greatest prevalence of alterations [3].

ZBTB20 GENIE Cases - Top Diseases

The most common alterations in ZBTB20 are ZBTB20 F671L (0.11%), ZBTB20 S89F (0.13%), ZBTB20 A40V (0.07%), ZBTB20 C583S (0.07%), and ZBTB20 D279N (0.09%) [3].

ZBTB20 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.