Overview

Location [1]
12q24.31
Protein [2]
Zinc finger CCHC domain-containing protein 8
Synonyms [1]
PFBMFT5

ZCCHC8 is altered in 0.10% of all cancers with lung adenocarcinoma, dedifferentiated liposarcoma, breast invasive ductal carcinoma, anaplastic ganglioglioma, and cancer of unknown primary, NOS having the greatest prevalence of alterations [3].

ZCCHC8 GENIE Cases - Top Diseases

The most common alteration in ZCCHC8 is ZCCHC8-ROS1 Fusion (0.10%) [3].

ZCCHC8 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.