Location [1]
Protein [2]
Multidrug resistance protein 1
Synonyms [1]
GP170, ABC20, CD243, P-GP, CLCS, MDR1, PGY1

ABCB1 is altered in 0.01% of all cancers with breast invasive ductal carcinoma having the greatest prevalence of alterations [3].

ABCB1 GENIE Cases - Top Diseases

The most common alterations in ABCB1 are ABCB1 Fusion (0.01%) and ABCB1-MYC Fusion (0.01%) [3].

ABCB1 GENIE Cases - Top Alterations

Significance of ABCB1 in Diseases

Ovarian Carcinoma +

Ovarian Carcinosarcoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.