Biomarkers /

ABCC4

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Overview

Location [1]
13q32.1
Protein [2]
Multidrug resistance-associated protein 4
Synonyms [1]
MRP4, MOATB, MOAT-B

ABCC4 is altered in 0.02% of all cancers with prostate adenocarcinoma, breast invasive lobular carcinoma, dedifferentiated liposarcoma, glioblastoma, and high grade ovarian serous adenocarcinoma having the greatest prevalence of alterations [3].

ABCC4 GENIE Cases - Top Diseases

The most common alteration in ABCC4 is ABCC4-ETV4 Fusion (0.05%) [3].

ABCC4 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.