Acyl-CoA synthetase long-chain family member 6 (ACSL6) is a gene that encodes a catalytic protein that is involved in the production of acyl-CoA from fatty acids, ATP, and CoA. The protein functions in fatty acid metabolism in the brain. Fusions, missense mutations, nonsense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.
Modified: July 1, 2015
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