Actin, beta (ACTB) is a gene that encodes a protein that functions in cell motility, structure, and integrity. The protein is also an important component of the contractile apparatus and one of two non-muscle cytoskeletal actins. Fusions, missense mutations, silent mutations, and frameshift insertions and deletions are observed in cancers such as salivary gland cancer, stomach cancer, and cancers of the urinary tract.
Modified: July 1, 2015
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