ACTL6A is altered in 0.09% of all cancers with colon adenocarcinoma, endometrial endometrioid adenocarcinoma, adenocarcinoma of the gastroesophageal junction, ampulla of vater carcinoma, and colorectal adenocarcinoma having the greatest prevalence of alterations .
The most common alteration in ACTL6A is ACTL6A-PIK3CA Fusion (0.09%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.