Location [1]
Protein [2]
Activin receptor type-2A
Synonyms [1]

ACVR2A is altered in 0.10% of all cancers with endometrial endometrioid adenocarcinoma, colon adenocarcinoma, ampulla of vater intestinal type adenocarcinoma, anaplastic astrocytoma, and cancer, NOS having the greatest prevalence of alterations [3].

ACVR2A GENIE Cases - Top Diseases

The most common alterations in ACVR2A are ACVR2A Mutation (0.82%), ACVR2A C16R (0.22%), ACVR2A D55V (0.22%), ACVR2A E72* (0.22%), and ACVR2A F33C (0.39%) [3].

ACVR2A GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.