Overview

Location [1]
7q32.1
Protein [2]
Adenosylhomocysteinase 3
Synonyms [1]
ADOHCYASE3, IRBIT2

AHCYL2 is altered in 0.05% of all cancers with astrocytoma, low-grade glioma, NOS, pancreatic adenocarcinoma, pilocytic astrocytoma, and thyroid gland papillary carcinoma having the greatest prevalence of alterations [3].

AHCYL2 GENIE Cases - Top Diseases

The most common alterations in AHCYL2 are AHCYL2-BRAF Fusion (0.14%) and AHCYL2-SMO Fusion (0.01%) [3].

AHCYL2 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.