Associated Genetic Biomarkers
Associated Diseases


Location [1]
Protein [2]
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms [1]
ARP-9, dJ494G10.1, ARCD, MDS019, A3G, CEM15, bK150C2.7, CEM-15, ARP9

APOBEC3G is altered in 0.47% of all cancers.

The most common alterations in APOBEC3G are APOBEC3G Mutation (0.02%), APOBEC3G F164Y (0.00%), APOBEC3G I266M (0.00%), APOBEC3G M295L (0.00%), and APOBEC3G N302Tfs*4 (0.00%) [3].

APOBEC3G GENIE Cases - Top Alterations

Significance of APOBEC3G in Diseases

Cancer +

Central Nervous System Neoplasm +

Cholangiocarcinoma +

Malignant Solid Tumor +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015.

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.