APP is altered in 0.39% of all cancers with breast invasive ductal carcinoma, adenocarcinoma of unknown primary, invasive breast carcinoma, bladder urothelial carcinoma, and colon adenocarcinoma having the greatest prevalence of alterations .
The most common alteration in APP is APP-NRG1 Fusion (0.39%) .
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3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.