AT rich interactive domain 1B (SWI 1-like) (ARID1B) is a gene that encodes a protein that is a component of the SWI/SNF chromatin remodeling complex. The protein functions in cell-cycle activation. Missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions and insertions are observed in cancers such as endometrial cancer, skin cancer, and stomach cancer.
Modified: July 1, 2015
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