AXL receptor tyrosine kinase (AXL) is a gene that encodes a protein that belongs to the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase family. The protein functions in cell signal transduction by binding to vitamin K-dependent protein growth arrest specific 6 (Gas6). Missense mutations, nonsense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as endometrial cancer, skin cancer, and stomach cancer.
Modified: July 1, 2015
Disclaimer: The information presented at MyCancerGenome.org is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.
