Beta-2-microglobulin (B2M) is a gene that encodes a serum protein associated with the major histocompatibility complex (MHC) class I heavy chain on cell surfaces. Missense mutations, frameshift deletions, nonsense mutations, synonymous mutations, frameshift insertions, inframe deletions, and complex mutations are observed in cancers such as colon cancer, stomach cancer, and hematopoietic and lymphoid cancers.
Modified: January 7, 2016
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