B-cell translocation gene 1, anti-proliferative (BTG1) is a gene that encodes a protein that belongs to an anti-proliferative gene family. The protein functions in the regulation of cell growth and differentiation by acting as a coactivator of cell differentiation. Fusions, missense mutations, nonsense mutations, silent mutations, and in-frame deletions are observed in cancers such as hematopoietic and lymphoid cancers, kidney cancer, and lung cancer.
Modified: July 1, 2015
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