Calmodulin binding transcription activator 1 (CAMTA1) is a gene that encodes a protein that functions in transcriptional regulation. Fusions, missense mutations, nonsense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.
CAMTA1 is altered in 0.04% of all cancers with epithelioid hemangioendothelioma, conventional glioblastoma multiforme, lung adenocarcinoma, breast invasive ductal carcinoma, and endometrial clear cell adenocarcinoma having the greatest prevalence of alterations .
The most common alterations in CAMTA1 are CAMTA1-WWTR1 Fusion (0.03%), CAMTA1 M107I (0.26%), CAMTA1-ERRFI1 Fusion (0.01%), and CAMTA1-TET1 Fusion (0.00%) .
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3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.