CARM1 is altered in 0.93% of all cancers with high grade ovarian serous adenocarcinoma, breast invasive ductal carcinoma, colon adenocarcinoma, endometrial endometrioid adenocarcinoma, and lung adenocarcinoma having the greatest prevalence of alterations .
The most common alterations in CARM1 are CARM1 Mutation (0.60%), CARM1 Amplification (0.42%), CARM1 Loss (0.10%), CARM1 R419W (0.02%), and CARM1 A590T (0.02%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.