Overview

Location [1]
19q13.41
Protein [2]
Myeloid cell surface antigen CD33
Synonyms [1]
SIGLEC3, SIGLEC-3, p67

Biomarker-Directed Therapies

Significance of CD33 in Diseases

Acute Myeloid Leukemia +

Myelodysplastic Syndromes +

Acute Biphenotypic Leukemia +

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome +

Acute Promyelocytic Leukemia +

Multiple Myeloma +

Refractory Anemia With Excess Blasts +

Secondary Acute Myeloid Leukemia +

Systemic Mastocytosis +

Therapy-Related Acute Myeloid Leukemia +

Therapy-Related Myelodysplastic Syndrome +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.