Associated Genetic Biomarkers
CD8A status serves as an inclusion eligibility criteria in 2 clinical trials, of which 2 are open and 0 are closed. Of the trials that contain CD8A status as an inclusion criterion, 1 is phase 1 (1 open) and 1 is phase 1/phase 2 (1 open).
Trials with CD8A status in the inclusion eligibility criteria most commonly target acute lymphoblastic leukemia and breast carcinoma .
The most frequent alteration to serve as an inclusion eligibility criterion is CD8A Expression .
Taa-specific t cells, camrelizumab, and nab-paclitaxel are the most frequent therapies in trials with CD8A as an inclusion criteria .
Significance of CD8A in Diseases
Acute Lymphoblastic Leukemia +
CD8A is an inclusion criterion in 1 clinical trial for acute lymphoblastic leukemia, of which 1 is open and 0 are closed. Of the trial that contains CD8A status and acute lymphoblastic leukemia as inclusion criteria, 1 is phase 1 (1 open) .
Breast Carcinoma +
CD8A is an inclusion criterion in 1 clinical trial for breast carcinoma, of which 1 is open and 0 are closed. Of the trial that contains CD8A status and breast carcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.