Overview

Location [1]
9q34.13
Protein [2]
Bile salt-activated lipase
Synonyms [1]
CEase, BSSL, LIPA, BAL, MODY8, CELL, BSDL, FAP, FAPP

CEL is altered in 0.05% of all cancers with sarcoma, NOS, breast invasive ductal carcinoma, gastric adenocarcinoma, oropharyngeal squamous cell carcinoma, and pancreatic acinar cell carcinoma having the greatest prevalence of alterations [3].

CEL GENIE Cases - Top Diseases

The most common alterations in CEL are CEL-NTRK1 Fusion (0.05%) and CEL-TSC1 Fusion (0.02%) [3].

CEL GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.