CEL is altered in 0.05% of all cancers with sarcoma, NOS, breast invasive ductal carcinoma, gastric adenocarcinoma, oropharyngeal squamous cell carcinoma, and pancreatic acinar cell carcinoma having the greatest prevalence of alterations .
The most common alterations in CEL are CEL-NTRK1 Fusion (0.05%) and CEL-TSC1 Fusion (0.02%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.