DEAD (Asp-Glu-Ala-Asp) box helicase 6 (DDX6) is a gene that encodes a protein that functions as an RNA helicase in P-bodies and stress granules. The protein is also involved in translation suppression, mRNA degradation, and microRNA-induced gene silencing. Fusions, missense mutations, nonsense mutations, silent mutations, and frameshift deletions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.
Modified: July 1, 2015
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